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Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius

These data are presented in support of structural and evolutionary analysis of the published article entitled “The occurrence of three D-J-C clusters within the dromedary TRB locus highlights a shared evolution in Tylopoda, Ruminantia and Suina” (Antonacci et al., 2017) [1]. Here we describe the gen...

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Autores principales: Antonacci, Rachele, Bellini, Mariagrazia, Castelli, Vito, Ciccarese, Salvatrice, Massari, Serafina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562110/
https://www.ncbi.nlm.nih.gov/pubmed/28856181
http://dx.doi.org/10.1016/j.dib.2017.08.002
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author Antonacci, Rachele
Bellini, Mariagrazia
Castelli, Vito
Ciccarese, Salvatrice
Massari, Serafina
author_facet Antonacci, Rachele
Bellini, Mariagrazia
Castelli, Vito
Ciccarese, Salvatrice
Massari, Serafina
author_sort Antonacci, Rachele
collection PubMed
description These data are presented in support of structural and evolutionary analysis of the published article entitled “The occurrence of three D-J-C clusters within the dromedary TRB locus highlights a shared evolution in Tylopoda, Ruminantia and Suina” (Antonacci et al., 2017) [1]. Here we describe the genomic structure and the gene content of the T cell receptor beta chain (TRB) locus in Camelus dromedarius. As in the other species of mammals, the general genomic organization of the dromedary TRB locus consists of a pool of TRBV genes located upstream of in tandem TRBD-J-C clusters, followed by a TRBV gene with an inverted transcriptional orientation. A peculiarity of the dromedary TRB locus structure is the presence of three TRBD-J-C clusters, which is a common feature of sheep, cattle and pig sequences.
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spelling pubmed-55621102017-08-30 Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius Antonacci, Rachele Bellini, Mariagrazia Castelli, Vito Ciccarese, Salvatrice Massari, Serafina Data Brief Immunology and Microbiology These data are presented in support of structural and evolutionary analysis of the published article entitled “The occurrence of three D-J-C clusters within the dromedary TRB locus highlights a shared evolution in Tylopoda, Ruminantia and Suina” (Antonacci et al., 2017) [1]. Here we describe the genomic structure and the gene content of the T cell receptor beta chain (TRB) locus in Camelus dromedarius. As in the other species of mammals, the general genomic organization of the dromedary TRB locus consists of a pool of TRBV genes located upstream of in tandem TRBD-J-C clusters, followed by a TRBV gene with an inverted transcriptional orientation. A peculiarity of the dromedary TRB locus structure is the presence of three TRBD-J-C clusters, which is a common feature of sheep, cattle and pig sequences. Elsevier 2017-08-03 /pmc/articles/PMC5562110/ /pubmed/28856181 http://dx.doi.org/10.1016/j.dib.2017.08.002 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Immunology and Microbiology
Antonacci, Rachele
Bellini, Mariagrazia
Castelli, Vito
Ciccarese, Salvatrice
Massari, Serafina
Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius
title Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius
title_full Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius
title_fullStr Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius
title_full_unstemmed Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius
title_short Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius
title_sort data characterizing the genomic structure of the t cell receptor (trb) locus in camelus dromedarius
topic Immunology and Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562110/
https://www.ncbi.nlm.nih.gov/pubmed/28856181
http://dx.doi.org/10.1016/j.dib.2017.08.002
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