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Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius
These data are presented in support of structural and evolutionary analysis of the published article entitled “The occurrence of three D-J-C clusters within the dromedary TRB locus highlights a shared evolution in Tylopoda, Ruminantia and Suina” (Antonacci et al., 2017) [1]. Here we describe the gen...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562110/ https://www.ncbi.nlm.nih.gov/pubmed/28856181 http://dx.doi.org/10.1016/j.dib.2017.08.002 |
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author | Antonacci, Rachele Bellini, Mariagrazia Castelli, Vito Ciccarese, Salvatrice Massari, Serafina |
author_facet | Antonacci, Rachele Bellini, Mariagrazia Castelli, Vito Ciccarese, Salvatrice Massari, Serafina |
author_sort | Antonacci, Rachele |
collection | PubMed |
description | These data are presented in support of structural and evolutionary analysis of the published article entitled “The occurrence of three D-J-C clusters within the dromedary TRB locus highlights a shared evolution in Tylopoda, Ruminantia and Suina” (Antonacci et al., 2017) [1]. Here we describe the genomic structure and the gene content of the T cell receptor beta chain (TRB) locus in Camelus dromedarius. As in the other species of mammals, the general genomic organization of the dromedary TRB locus consists of a pool of TRBV genes located upstream of in tandem TRBD-J-C clusters, followed by a TRBV gene with an inverted transcriptional orientation. A peculiarity of the dromedary TRB locus structure is the presence of three TRBD-J-C clusters, which is a common feature of sheep, cattle and pig sequences. |
format | Online Article Text |
id | pubmed-5562110 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-55621102017-08-30 Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius Antonacci, Rachele Bellini, Mariagrazia Castelli, Vito Ciccarese, Salvatrice Massari, Serafina Data Brief Immunology and Microbiology These data are presented in support of structural and evolutionary analysis of the published article entitled “The occurrence of three D-J-C clusters within the dromedary TRB locus highlights a shared evolution in Tylopoda, Ruminantia and Suina” (Antonacci et al., 2017) [1]. Here we describe the genomic structure and the gene content of the T cell receptor beta chain (TRB) locus in Camelus dromedarius. As in the other species of mammals, the general genomic organization of the dromedary TRB locus consists of a pool of TRBV genes located upstream of in tandem TRBD-J-C clusters, followed by a TRBV gene with an inverted transcriptional orientation. A peculiarity of the dromedary TRB locus structure is the presence of three TRBD-J-C clusters, which is a common feature of sheep, cattle and pig sequences. Elsevier 2017-08-03 /pmc/articles/PMC5562110/ /pubmed/28856181 http://dx.doi.org/10.1016/j.dib.2017.08.002 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Immunology and Microbiology Antonacci, Rachele Bellini, Mariagrazia Castelli, Vito Ciccarese, Salvatrice Massari, Serafina Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius |
title | Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius |
title_full | Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius |
title_fullStr | Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius |
title_full_unstemmed | Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius |
title_short | Data characterizing the genomic structure of the T cell receptor (TRB) locus in Camelus dromedarius |
title_sort | data characterizing the genomic structure of the t cell receptor (trb) locus in camelus dromedarius |
topic | Immunology and Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562110/ https://www.ncbi.nlm.nih.gov/pubmed/28856181 http://dx.doi.org/10.1016/j.dib.2017.08.002 |
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