Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism

The growing field of cardio-oncology addresses the side effects of cancer treatment on the cardiovascular system. Here, we explored the cardiotoxicity of the antiangiogenic therapy, sunitinib, in the mouse heart from a diagnostic and therapeutic perspective. We showed that sunitinib induces an anaer...

Descripción completa

Detalles Bibliográficos
Autores principales: Sourdon, Joevin, Lager, Franck, Viel, Thomas, Balvay, Daniel, Moorhouse, Rebecca, Bennana, Evangeline, Renault, Gilles, Tharaux, Pierre-Louis, Dhaun, Neeraj, Tavitian, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562214/
https://www.ncbi.nlm.nih.gov/pubmed/28824714
http://dx.doi.org/10.7150/thno.19551

Ejemplares similares

Ejemplares similares