Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin

Cysteine cathepsins often contribute to cancer progression due to their overexpression in the tumour microenvironment and therefore present attractive targets for non-invasive diagnostic imaging. However, the development of highly selective and versatile small molecule probes for cathepsins has been...

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Detalles Bibliográficos
Autores principales: Kramer, Lovro, Renko, Miha, Završnik, Janja, Turk, Dušan, Seeger, Markus A., Vasiljeva, Olga, Grütter, Markus G., Turk, Vito, Turk, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562217/
https://www.ncbi.nlm.nih.gov/pubmed/28824717
http://dx.doi.org/10.7150/thno.19081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562217/
https://www.ncbi.nlm.nih.gov/pubmed/28824717
http://dx.doi.org/10.7150/thno.19081

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