Cargando…
Non-invasive in vivo imaging of tumour-associated cathepsin B by a highly selective inhibitory DARPin
Cysteine cathepsins often contribute to cancer progression due to their overexpression in the tumour microenvironment and therefore present attractive targets for non-invasive diagnostic imaging. However, the development of highly selective and versatile small molecule probes for cathepsins has been...
Autores principales: | Kramer, Lovro, Renko, Miha, Završnik, Janja, Turk, Dušan, Seeger, Markus A., Vasiljeva, Olga, Grütter, Markus G., Turk, Vito, Turk, Boris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562217/ https://www.ncbi.nlm.nih.gov/pubmed/28824717 http://dx.doi.org/10.7150/thno.19081 |
Ejemplares similares
-
Cysteine cathepsins: From structure, function and regulation to new frontiers()
por: Turk, Vito, et al.
Publicado: (2012) -
Cystatin C deficiency suppresses tumor growth in a breast cancer model through decreased proliferation of tumor cells
por: Završnik, Janja, et al.
Publicado: (2017) -
Evaluation of novel cathepsin-X inhibitors in vitro and in vivo and their ability to improve cathepsin-B-directed antitumor therapy
por: Mitrović, Ana, et al.
Publicado: (2022) -
In vivo imaging of Lactococcus lactis, Lactobacillus plantarum and Escherichia coli expressing infrared fluorescent protein in mice
por: Berlec, Aleš, et al.
Publicado: (2015) -
Differential Impact of Cysteine Cathepsins on Genetic Mouse Models of De novo Carcinogenesis: Cathepsin B as Emerging Therapeutic Target
por: Reinheckel, Thomas, et al.
Publicado: (2012)