Defective replication stress response inhibits lymphomagenesis and impairs lymphocyte reconstitution

DNA replication stress promotes genome instability in cancer. However, the contribution of the replication stress response to the development of malignancies remains unresolved. The DNA replication stress response protein SMARCAL1 stabilizes DNA replication forks and prevents replication fork collap...

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Detalles Bibliográficos
Autores principales: Puccetti, Matthew V., Fischer, Melissa A., Arrate, Maria Pia, Boyd, Kelli L., Duszynski, Robert J., Bétous, Rémy, Cortez, David, Eischen, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562353/
https://www.ncbi.nlm.nih.gov/pubmed/27797382
http://dx.doi.org/10.1038/onc.2016.408

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