The metabolomics of psoriatic disease

Metabolomics is an emerging new “omics” field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes in metabolic pathways that drive disease. Recen...

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Autores principales: Yan, Di, Afifi, Ladan, Jeon, Caleb, Trivedi, Megha, Chang, Hsin Wen, Lee, Kristina, Liao, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562362/
https://www.ncbi.nlm.nih.gov/pubmed/28824870
http://dx.doi.org/10.2147/PTT.S118348
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author Yan, Di
Afifi, Ladan
Jeon, Caleb
Trivedi, Megha
Chang, Hsin Wen
Lee, Kristina
Liao, Wilson
author_facet Yan, Di
Afifi, Ladan
Jeon, Caleb
Trivedi, Megha
Chang, Hsin Wen
Lee, Kristina
Liao, Wilson
author_sort Yan, Di
collection PubMed
description Metabolomics is an emerging new “omics” field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes in metabolic pathways that drive disease. Recently, metabolomics has been used to study the local and systemic metabolic changes in psoriasis and its cardiometabolic comorbidities. Such studies have revealed novel insights into disease pathogenesis and suggest new biochemical signatures that may be used as a marker of psoriatic disease. This review will discuss common strategies in metabolomics analysis, current findings in the metabolomics of psoriasis, and emerging trends in psoriatic metabolomics.
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spelling pubmed-55623622017-08-18 The metabolomics of psoriatic disease Yan, Di Afifi, Ladan Jeon, Caleb Trivedi, Megha Chang, Hsin Wen Lee, Kristina Liao, Wilson Psoriasis (Auckl) Review Metabolomics is an emerging new “omics” field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes in metabolic pathways that drive disease. Recently, metabolomics has been used to study the local and systemic metabolic changes in psoriasis and its cardiometabolic comorbidities. Such studies have revealed novel insights into disease pathogenesis and suggest new biochemical signatures that may be used as a marker of psoriatic disease. This review will discuss common strategies in metabolomics analysis, current findings in the metabolomics of psoriasis, and emerging trends in psoriatic metabolomics. Dove Medical Press 2017-01-31 /pmc/articles/PMC5562362/ /pubmed/28824870 http://dx.doi.org/10.2147/PTT.S118348 Text en © 2017 Yan et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Yan, Di
Afifi, Ladan
Jeon, Caleb
Trivedi, Megha
Chang, Hsin Wen
Lee, Kristina
Liao, Wilson
The metabolomics of psoriatic disease
title The metabolomics of psoriatic disease
title_full The metabolomics of psoriatic disease
title_fullStr The metabolomics of psoriatic disease
title_full_unstemmed The metabolomics of psoriatic disease
title_short The metabolomics of psoriatic disease
title_sort metabolomics of psoriatic disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562362/
https://www.ncbi.nlm.nih.gov/pubmed/28824870
http://dx.doi.org/10.2147/PTT.S118348
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