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Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin

As the central hub of the metabolism machinery, the mammalian target of rapamycin complex 2 (mTORC2) has been well studied in lymphocytes. As an obligatory component of mTORC2, the role of Rictor in T cells is well established. However, the role of Rictor in B cells still remains elusive. Rictor is...

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Detalles Bibliográficos
Autores principales: Huang, Lu, Zhang, Yongjie, Xu, Chenguang, Gu, Xiaomei, Niu, Linlin, Wang, Jinzhi, Sun, Xiaoyu, Bai, Xiaoming, Xuan, Xingtian, Li, Qubei, Shi, Chunwei, Yu, Bing, Miller, Heather, Yang, Gangyi, Westerberg, Lisa S., Liu, Wanli, Song, Wenxia, Zhao, Xiaodong, Liu, Chaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562439/
https://www.ncbi.nlm.nih.gov/pubmed/28821013
http://dx.doi.org/10.1371/journal.pbio.2001750