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In vitro analysis of RQC activities provides insights into the mechanism and function of CAT tailing

Ribosomes can stall during translation due to defects in the mRNA template or translation machinery, leading to the production of incomplete proteins. The Ribosome-associated Quality control Complex (RQC) engages stalled ribosomes and targets nascent polypeptides for proteasomal degradation. However...

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Detalles Bibliográficos
Autores principales:	Osuna, Beatriz A, Howard, Conor J, KC, Subheksha, Frost, Adam, Weinberg, David E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562442/ https://www.ncbi.nlm.nih.gov/pubmed/28718767 http://dx.doi.org/10.7554/eLife.27949

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