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Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

Acquired therapeutic resistance by tumors is a substantial impediment to reducing the morbidity and mortality that are attributable to human malignancies. The mechanisms responsible for the dramatic shift between chemosensitivity and chemoresistance in colorectal carcinoma have not been defined. Her...

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Detalles Bibliográficos
Autores principales:	Li, Xiaolei, Wu, Zhiqiang, An, Xiaojing, Mei, Qian, Bai, Miaomiao, Hanski, Leena, Li, Xiang, Ahola, Tero, Han, Weidong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562444/ https://www.ncbi.nlm.nih.gov/pubmed/28820388 http://dx.doi.org/10.7554/eLife.27301

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