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Failure to Deliver and Translate—New Insights into RNA Dysregulation in ALS

Amyotrophic Lateral Sclerosis (ALS) is a progressive and fatal neurodegenerative disease affecting both upper and lower motor neurons. The molecular mechanisms underlying disease pathogenesis remain largely unknown. Multiple genetic loci including genes involved in proteostasis and ribostasis have b...

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Detalles Bibliográficos
Autores principales:	Coyne, Alyssa N., Zaepfel, Benjamin L., Zarnescu, Daniela C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562674/ https://www.ncbi.nlm.nih.gov/pubmed/28860970 http://dx.doi.org/10.3389/fncel.2017.00243

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