Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation

The biogenesis of autophagosomes depends on the conjugation of Atg8-like proteins with phosphatidylethanolamine. Atg8 processing by the cysteine protease Atg4 is required for its covalent linkage to phosphatidylethanolamine, but it is also necessary for Atg8 deconjugation from this lipid to release...

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Detalles Bibliográficos
Autores principales: Sánchez-Wandelmer, Jana, Kriegenburg, Franziska, Rohringer, Sabrina, Schuschnig, Martina, Gómez-Sánchez, Rubén, Zens, Bettina, Abreu, Susana, Hardenberg, Ralph, Hollenstein, David, Gao, Jieqiong, Ungermann, Christian, Martens, Sascha, Kraft, Claudine, Reggiori, Fulvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562703/
https://www.ncbi.nlm.nih.gov/pubmed/28821724
http://dx.doi.org/10.1038/s41467-017-00302-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562703/
https://www.ncbi.nlm.nih.gov/pubmed/28821724
http://dx.doi.org/10.1038/s41467-017-00302-3

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