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ROCK-1 mediates diabetes-induced retinal pigment epithelial and endothelial cell blebbing: Contribution to diabetic retinopathy

In diabetic retinopathy, the exact mechanisms leading to retinal capillary closure and to retinal barriers breakdown remain imperfectly understood. Rho-associated kinase (ROCK), an effector of the small GTPase Rho, involved in cytoskeleton dynamic regulation and cell polarity is activated by hypergl...

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Detalles Bibliográficos
Autores principales:	Rothschild, Pierre-Raphaël, Salah, Sawsen, Berdugo, Marianne, Gélizé, Emmanuelle, Delaunay, Kimberley, Naud, Marie-Christine, Klein, Christophe, Moulin, Alexandre, Savoldelli, Michèle, Bergin, Ciara, Jeanny, Jean-Claude, Jonet, Laurent, Arsenijevic, Yvan, Behar-Cohen, Francine, Crisanti, Patricia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562711/ https://www.ncbi.nlm.nih.gov/pubmed/28821742 http://dx.doi.org/10.1038/s41598-017-07329-y

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