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Isolation of Single-Domain Antibody Fragments That Preferentially Detect Intact (146S) Particles of Foot-and-Mouth Disease Virus for Use in Vaccine Quality Control

Intact (146S) foot-and-mouth disease virus (FMDVs) can dissociate into specific (12S) viral capsid degradation products. FMD vaccines normally consist of inactivated virions. Vaccine quality is dependent on 146S virus particles rather than 12S particles. We earlier isolated two llama single-domain a...

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Detalles Bibliográficos
Autores principales:	Harmsen, Michiel M., Seago, Julian, Perez, Eva, Charleston, Bryan, Eblé, Phaedra L., Dekker, Aldo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562729/ https://www.ncbi.nlm.nih.gov/pubmed/28861080 http://dx.doi.org/10.3389/fimmu.2017.00960

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