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Phase I/II clinical trial to assess safety and efficacy of intratumoral and subcutaneous injection of HVJ-E in castration-resistant prostate cancer patients
Inactivated Sendai virus particles (hemagglutinating virus of Japan envelope (HVJ-E)) have a novel antitumor effect: HVJ-E fused to prostate cancer cells via cell surface receptor causes apoptosis of prostate cancer cells in vitro and in vivo. HVJ-E also induces antitumor immunity by activating natu...
Autores principales: | Fujita, K, Nakai, Y, Kawashima, A, Ujike, T, Nagahara, A, Nakajima, T, Inoue, T, Lee, C M, Uemura, M, Miyagawa, Y, Kaneda, Y, Nonomura, N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562845/ https://www.ncbi.nlm.nih.gov/pubmed/28497777 http://dx.doi.org/10.1038/cgt.2017.15 |
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