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New factors in mammalian DNA repair—the chromatin connection

In response to DNA damage mammalian cells activate a complex network of stress response pathways collectively termed DNA damage response (DDR). DDR involves a temporary arrest of the cell cycle to allow for the repair of the damage. DDR also attenuates gene expression by silencing global transcripti...

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Detalles Bibliográficos
Autores principales: Raschellà, G, Melino, G, Malewicz, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562846/
https://www.ncbi.nlm.nih.gov/pubmed/28394347
http://dx.doi.org/10.1038/onc.2017.60