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Nanomechanics of multidomain neuronal cell adhesion protein contactin revealed by single molecule AFM and SMD
Contactin-4 (CNTN4) is a complex cell adhesion molecule (CAM) localized at neuronal membranes, playing a key role in maintaining the mechanical integrity and signaling properties of the synapse. CNTN4 consists of six immunoglobulin C2 type (IgC2) domains and four fibronectin type III (FnIII) domains...
Autores principales: | Mikulska-Ruminska, Karolina, Kulik, Andrej J., Benadiba, Carine, Bahar, Ivet, Dietler, Giovanni, Nowak, Wieslaw |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562865/ https://www.ncbi.nlm.nih.gov/pubmed/28821864 http://dx.doi.org/10.1038/s41598-017-09482-w |
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