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Promysalin is a salicylate-containing antimicrobial with a cell-membrane-disrupting mechanism of action on Gram-positive bacteria

Promysalin was previously described as a narrow spectrum molecule with a unique species-specific activity against Pseudomonas aeruginosa. Here we demonstrate that promysalin is active against Gram-positive and Gram-negative bacteria using a microdilution assay. Promysalin acts on Gram-positive bacte...

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Detalles Bibliográficos
Autores principales: Kaduskar, Rahul D., Scala, Giulia Della, Al Jabri, Zaaima J. H., Arioli, Stefania, Musso, Loana, Oggioni, Marco R., Dallavalle, Sabrina, Mora, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562885/
https://www.ncbi.nlm.nih.gov/pubmed/28821717
http://dx.doi.org/10.1038/s41598-017-07567-0