Adaptive from Innate: Human IFN-γ(+)CD4(+) T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults

We recently demonstrated that the major effector function of neonatal CD4(+) T cells is to produce CXCL8, a prototypic cytokine of innate immune cells. In this article, we show that CXCL8 expression, prior to proliferation, is common in newly arising T cells (so-called “recent thymic emigrants”) in...

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Detalles Bibliográficos
Autores principales: Das, Abhishek, Rouault-Pierre, Kevin, Kamdar, Shraddha, Gomez-Tourino, Iria, Wood, Kristie, Donaldson, Ian, Mein, Charles A., Bonnet, Dominique, Hayday, Adrian C., Gibbons, Deena L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2017
Materias:
Immune System Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563168/
https://www.ncbi.nlm.nih.gov/pubmed/28754679
http://dx.doi.org/10.4049/jimmunol.1700551

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