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Altered purinergic signaling in uridine adenosine tetraphosphate-induced coronary relaxation in swine with metabolic derangement

We previously demonstrated that uridine adenosine tetraphosphate (Up(4)A) induces potent and partially endothelium-dependent relaxation in the healthy porcine coronary microvasculature. We subsequently showed that Up(4)A-induced porcine coronary relaxation was impaired via downregulation of P1 recep...

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Detalles Bibliográficos
Autores principales: Zhou, Zhichao, Sorop, Oana, de Beer, Vincent J., Heinonen, Ilkka, Cheng, Caroline, Jan Danser, A. H., Duncker, Dirk J., Merkus, Daphne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563292/
https://www.ncbi.nlm.nih.gov/pubmed/28540569
http://dx.doi.org/10.1007/s11302-017-9563-6

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