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Altered purinergic signaling in uridine adenosine tetraphosphate-induced coronary relaxation in swine with metabolic derangement
We previously demonstrated that uridine adenosine tetraphosphate (Up(4)A) induces potent and partially endothelium-dependent relaxation in the healthy porcine coronary microvasculature. We subsequently showed that Up(4)A-induced porcine coronary relaxation was impaired via downregulation of P1 recep...
Autores principales: | Zhou, Zhichao, Sorop, Oana, de Beer, Vincent J., Heinonen, Ilkka, Cheng, Caroline, Jan Danser, A. H., Duncker, Dirk J., Merkus, Daphne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563292/ https://www.ncbi.nlm.nih.gov/pubmed/28540569 http://dx.doi.org/10.1007/s11302-017-9563-6 |
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