Fast assembling of neuron fragments in serial 3D sections

Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3...

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Detalles Bibliográficos
Autores principales: Chen, Hanbo, Iascone, Daniel Maxim, da Costa, Nuno Maçarico, Lein, Ed S., Liu, Tianming, Peng, Hanchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563299/
https://www.ncbi.nlm.nih.gov/pubmed/28365869
http://dx.doi.org/10.1007/s40708-017-0063-9
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author Chen, Hanbo
Iascone, Daniel Maxim
da Costa, Nuno Maçarico
Lein, Ed S.
Liu, Tianming
Peng, Hanchuan
author_facet Chen, Hanbo
Iascone, Daniel Maxim
da Costa, Nuno Maçarico
Lein, Ed S.
Liu, Tianming
Peng, Hanchuan
author_sort Chen, Hanbo
collection PubMed
description Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s40708-017-0063-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-55632992017-09-01 Fast assembling of neuron fragments in serial 3D sections Chen, Hanbo Iascone, Daniel Maxim da Costa, Nuno Maçarico Lein, Ed S. Liu, Tianming Peng, Hanchuan Brain Inform Article Reconstructing neurons from 3D image-stacks of serial sections of thick brain tissue is very time-consuming and often becomes a bottleneck in high-throughput brain mapping projects. We developed NeuronStitcher, a software suite for stitching non-overlapping neuron fragments reconstructed in serial 3D image sections. With its efficient algorithm and user-friendly interface, NeuronStitcher has been used successfully to reconstruct very large and complex human and mouse neurons. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s40708-017-0063-9) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2017-04-01 /pmc/articles/PMC5563299/ /pubmed/28365869 http://dx.doi.org/10.1007/s40708-017-0063-9 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Article
Chen, Hanbo
Iascone, Daniel Maxim
da Costa, Nuno Maçarico
Lein, Ed S.
Liu, Tianming
Peng, Hanchuan
Fast assembling of neuron fragments in serial 3D sections
title Fast assembling of neuron fragments in serial 3D sections
title_full Fast assembling of neuron fragments in serial 3D sections
title_fullStr Fast assembling of neuron fragments in serial 3D sections
title_full_unstemmed Fast assembling of neuron fragments in serial 3D sections
title_short Fast assembling of neuron fragments in serial 3D sections
title_sort fast assembling of neuron fragments in serial 3d sections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563299/
https://www.ncbi.nlm.nih.gov/pubmed/28365869
http://dx.doi.org/10.1007/s40708-017-0063-9
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