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3D brain Organoids derived from pluripotent stem cells: promising experimental models for brain development and neurodegenerative disorders

Three-dimensional (3D) brain organoids derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), appear to recapitulate the brain’s 3D cytoarchitectural arrangement and provide new opportunities to explore disease pathogenesi...

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Detalles Bibliográficos
Autores principales: Lee, Chun-Ting, Bendriem, Raphael M., Wu, Wells W., Shen, Rong-Fong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563385/
https://www.ncbi.nlm.nih.gov/pubmed/28822354
http://dx.doi.org/10.1186/s12929-017-0362-8