Cargando…
Increased Circulating Levels of Interleukin-6 Induce Perturbation in Redox-Regulated Signaling Cascades in Muscle of Dystrophic Mice
Duchenne muscular dystrophy (DMD) is an X-linked genetic disease in which dystrophin gene is mutated, resulting in dysfunctional or absent dystrophin protein. The pathology of dystrophic muscle includes degeneration, necrosis with inflammatory cell invasion, regeneration, and fibrous and fatty chang...
Autores principales: | Pelosi, Laura, Forcina, Laura, Nicoletti, Carmine, Scicchitano, Bianca Maria, Musarò, Antonio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563418/ https://www.ncbi.nlm.nih.gov/pubmed/28845212 http://dx.doi.org/10.1155/2017/1987218 |
Ejemplares similares
-
Increased Circulating Levels of Interleukin-6 Affect the Redox Balance in Skeletal Muscle
por: Forcina, Laura, et al.
Publicado: (2019) -
Increased levels of interleukin-6 exacerbate the dystrophic phenotype in mdx mice
por: Pelosi, Laura, et al.
Publicado: (2015) -
Functional and Morphological Improvement of Dystrophic Muscle by Interleukin 6 Receptor Blockade
por: Pelosi, Laura, et al.
Publicado: (2015) -
MicroRNAs modulated by local mIGF-1 expression in mdx dystrophic mice
por: Pelosi, Laura, et al.
Publicado: (2015) -
Signals from the Niche: Insights into the Role of IGF-1 and IL-6 in Modulating Skeletal Muscle Fibrosis
por: Forcina, Laura, et al.
Publicado: (2019)