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Developmental Changes in Sleep Oscillations during Early Childhood

Although quantitative analysis of the sleep electroencephalogram (EEG) has uncovered important aspects of brain activity during sleep in adolescents and adults, similar findings from preschool-age children remain scarce. This study utilized our time-frequency method to examine sleep oscillations as...

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Autores principales: Olbrich, Eckehard, Rusterholz, Thomas, LeBourgeois, Monique K., Achermann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563422/
https://www.ncbi.nlm.nih.gov/pubmed/28845310
http://dx.doi.org/10.1155/2017/6160959
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author Olbrich, Eckehard
Rusterholz, Thomas
LeBourgeois, Monique K.
Achermann, Peter
author_facet Olbrich, Eckehard
Rusterholz, Thomas
LeBourgeois, Monique K.
Achermann, Peter
author_sort Olbrich, Eckehard
collection PubMed
description Although quantitative analysis of the sleep electroencephalogram (EEG) has uncovered important aspects of brain activity during sleep in adolescents and adults, similar findings from preschool-age children remain scarce. This study utilized our time-frequency method to examine sleep oscillations as characteristic features of human sleep EEG. Data were collected from a longitudinal sample of young children (n = 8; 3 males) at ages 2, 3, and 5 years. Following sleep stage scoring, we detected and characterized oscillatory events across age and examined how their features corresponded to spectral changes in the sleep EEG. Results indicated a developmental decrease in the incidence of delta and theta oscillations. Spindle oscillations, however, were almost absent at 2 years but pronounced at 5 years. All oscillatory event changes were stronger during light sleep than slow-wave sleep. Large interindividual differences in sleep oscillations and their characteristics (e.g., “ultrafast” spindle-like oscillations, theta oscillation incidence/frequency) also existed. Changes in delta and spindle oscillations across early childhood may indicate early maturation of the thalamocortical system. Our analytic approach holds promise for revealing novel types of sleep oscillatory events that are specific to periods of rapid normal development across the lifespan and during other times of aberrant changes in neurobehavioral function.
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spelling pubmed-55634222017-08-27 Developmental Changes in Sleep Oscillations during Early Childhood Olbrich, Eckehard Rusterholz, Thomas LeBourgeois, Monique K. Achermann, Peter Neural Plast Research Article Although quantitative analysis of the sleep electroencephalogram (EEG) has uncovered important aspects of brain activity during sleep in adolescents and adults, similar findings from preschool-age children remain scarce. This study utilized our time-frequency method to examine sleep oscillations as characteristic features of human sleep EEG. Data were collected from a longitudinal sample of young children (n = 8; 3 males) at ages 2, 3, and 5 years. Following sleep stage scoring, we detected and characterized oscillatory events across age and examined how their features corresponded to spectral changes in the sleep EEG. Results indicated a developmental decrease in the incidence of delta and theta oscillations. Spindle oscillations, however, were almost absent at 2 years but pronounced at 5 years. All oscillatory event changes were stronger during light sleep than slow-wave sleep. Large interindividual differences in sleep oscillations and their characteristics (e.g., “ultrafast” spindle-like oscillations, theta oscillation incidence/frequency) also existed. Changes in delta and spindle oscillations across early childhood may indicate early maturation of the thalamocortical system. Our analytic approach holds promise for revealing novel types of sleep oscillatory events that are specific to periods of rapid normal development across the lifespan and during other times of aberrant changes in neurobehavioral function. Hindawi 2017 2017-08-15 /pmc/articles/PMC5563422/ /pubmed/28845310 http://dx.doi.org/10.1155/2017/6160959 Text en Copyright © 2017 Eckehard Olbrich et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Olbrich, Eckehard
Rusterholz, Thomas
LeBourgeois, Monique K.
Achermann, Peter
Developmental Changes in Sleep Oscillations during Early Childhood
title Developmental Changes in Sleep Oscillations during Early Childhood
title_full Developmental Changes in Sleep Oscillations during Early Childhood
title_fullStr Developmental Changes in Sleep Oscillations during Early Childhood
title_full_unstemmed Developmental Changes in Sleep Oscillations during Early Childhood
title_short Developmental Changes in Sleep Oscillations during Early Childhood
title_sort developmental changes in sleep oscillations during early childhood
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563422/
https://www.ncbi.nlm.nih.gov/pubmed/28845310
http://dx.doi.org/10.1155/2017/6160959
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