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ROCKII inhibition promotes the maturation of human pancreatic beta-like cells

Diabetes is linked to loss of pancreatic beta-cells. Pluripotent stem cells offer a valuable source of human beta-cells for basic studies of their biology and translational applications. However, the signalling pathways that regulate beta-cell development and functional maturation are not fully unde...

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Detalles Bibliográficos
Autores principales:	Ghazizadeh, Zaniar, Kao, Der-I, Amin, Sadaf, Cook, Brandoch, Rao, Sahana, Zhou, Ting, Zhang, Tuo, Xiang, Zhaoying, Kenyon, Reyn, Kaymakcalan, Omer, Liu, Chengyang, Evans, Todd, Chen, Shuibing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563509/ https://www.ncbi.nlm.nih.gov/pubmed/28824164 http://dx.doi.org/10.1038/s41467-017-00129-y

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