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Systematic evaluation of monoclonal antibodies and immunoassays for the detection of Interferon-γ and Interleukin-2 in old and new world non-human primates

Non-human primates (NHP) provide important animal models for studies on immune responses to infections and vaccines. When assessing cellular immunity in NHP, cytokines are almost exclusively analyzed utilizing cross-reactive anti-human antibodies. The functionality of antibodies has to be empiricall...

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Detalles Bibliográficos
Autores principales: Höglind, Ankie, Areström, Irene, Ehrnfelt, Cecilia, Masjedi, Khosro, Zuber, Bartek, Giavedoni, Luis, Ahlborg, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563966/
https://www.ncbi.nlm.nih.gov/pubmed/27889562
http://dx.doi.org/10.1016/j.jim.2016.11.011