Cargando…

Baseline Demographic and Clinical Characteristics of Patients with Adrenal Incidentaloma from a Single Center in China: A Survey

AIM: To investigate the clinical and endocrinological characteristics of patients with adrenal incidentaloma (AI). MATERIALS AND METHODS: This retrospective study enrolled 1941 AI patients hospitalized at the Department of Endocrinology, Chinese PLA General Hospital, Beijing, China, between January...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Lele, Yang, Guoqing, Zhao, Ling, Dou, Jingtao, Gu, Weijun, Lv, Zhaohui, Lu, Juming, Mu, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564109/
https://www.ncbi.nlm.nih.gov/pubmed/28848603
http://dx.doi.org/10.1155/2017/3093290
_version_ 1783258207087493120
author Li, Lele
Yang, Guoqing
Zhao, Ling
Dou, Jingtao
Gu, Weijun
Lv, Zhaohui
Lu, Juming
Mu, Yiming
author_facet Li, Lele
Yang, Guoqing
Zhao, Ling
Dou, Jingtao
Gu, Weijun
Lv, Zhaohui
Lu, Juming
Mu, Yiming
author_sort Li, Lele
collection PubMed
description AIM: To investigate the clinical and endocrinological characteristics of patients with adrenal incidentaloma (AI). MATERIALS AND METHODS: This retrospective study enrolled 1941 AI patients hospitalized at the Department of Endocrinology, Chinese PLA General Hospital, Beijing, China, between January 1997 and December 2016. The patient gender, age at visits, imaging features, functional status, and histological results were analyzed. RESULTS: Of the 1941 patients, 984 (50.70%) were men. The median age was 52 years (interquartile range: 44–69 years). 140 cases had bilateral AI. Endocrine evaluation showed that 1411 (72.69%) patients had nonfunctional tumor, 152 (7.83%) had subclinical Cushing syndrome (SCS), and 82 (4.33%) had primary hyperaldosteronism. A total of 925 patients underwent operation for removal of 496 cortical adenomas (53.62%), 15 adrenal cortical carcinomas (1.62%), and 172 pheochromocytomas (18.59%). The bilateral group had a higher proportion of SCS (18.57% versus 7.10%, P < 0.001, P = 0.006). A mass size of 46 mm was of great value in distinguishing malignant tumors from the benign tumors, with sensitivity of 88.2% and specificity of 95.5%. CONCLUSIONS: We reported the baseline demographic and clinical characteristics of patients with AI in a large series from a single center in China.
format Online
Article
Text
id pubmed-5564109
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-55641092017-08-28 Baseline Demographic and Clinical Characteristics of Patients with Adrenal Incidentaloma from a Single Center in China: A Survey Li, Lele Yang, Guoqing Zhao, Ling Dou, Jingtao Gu, Weijun Lv, Zhaohui Lu, Juming Mu, Yiming Int J Endocrinol Research Article AIM: To investigate the clinical and endocrinological characteristics of patients with adrenal incidentaloma (AI). MATERIALS AND METHODS: This retrospective study enrolled 1941 AI patients hospitalized at the Department of Endocrinology, Chinese PLA General Hospital, Beijing, China, between January 1997 and December 2016. The patient gender, age at visits, imaging features, functional status, and histological results were analyzed. RESULTS: Of the 1941 patients, 984 (50.70%) were men. The median age was 52 years (interquartile range: 44–69 years). 140 cases had bilateral AI. Endocrine evaluation showed that 1411 (72.69%) patients had nonfunctional tumor, 152 (7.83%) had subclinical Cushing syndrome (SCS), and 82 (4.33%) had primary hyperaldosteronism. A total of 925 patients underwent operation for removal of 496 cortical adenomas (53.62%), 15 adrenal cortical carcinomas (1.62%), and 172 pheochromocytomas (18.59%). The bilateral group had a higher proportion of SCS (18.57% versus 7.10%, P < 0.001, P = 0.006). A mass size of 46 mm was of great value in distinguishing malignant tumors from the benign tumors, with sensitivity of 88.2% and specificity of 95.5%. CONCLUSIONS: We reported the baseline demographic and clinical characteristics of patients with AI in a large series from a single center in China. Hindawi 2017 2017-08-07 /pmc/articles/PMC5564109/ /pubmed/28848603 http://dx.doi.org/10.1155/2017/3093290 Text en Copyright © 2017 Lele Li et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Li, Lele
Yang, Guoqing
Zhao, Ling
Dou, Jingtao
Gu, Weijun
Lv, Zhaohui
Lu, Juming
Mu, Yiming
Baseline Demographic and Clinical Characteristics of Patients with Adrenal Incidentaloma from a Single Center in China: A Survey
title Baseline Demographic and Clinical Characteristics of Patients with Adrenal Incidentaloma from a Single Center in China: A Survey
title_full Baseline Demographic and Clinical Characteristics of Patients with Adrenal Incidentaloma from a Single Center in China: A Survey
title_fullStr Baseline Demographic and Clinical Characteristics of Patients with Adrenal Incidentaloma from a Single Center in China: A Survey
title_full_unstemmed Baseline Demographic and Clinical Characteristics of Patients with Adrenal Incidentaloma from a Single Center in China: A Survey
title_short Baseline Demographic and Clinical Characteristics of Patients with Adrenal Incidentaloma from a Single Center in China: A Survey
title_sort baseline demographic and clinical characteristics of patients with adrenal incidentaloma from a single center in china: a survey
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564109/
https://www.ncbi.nlm.nih.gov/pubmed/28848603
http://dx.doi.org/10.1155/2017/3093290
work_keys_str_mv AT lilele baselinedemographicandclinicalcharacteristicsofpatientswithadrenalincidentalomafromasinglecenterinchinaasurvey
AT yangguoqing baselinedemographicandclinicalcharacteristicsofpatientswithadrenalincidentalomafromasinglecenterinchinaasurvey
AT zhaoling baselinedemographicandclinicalcharacteristicsofpatientswithadrenalincidentalomafromasinglecenterinchinaasurvey
AT doujingtao baselinedemographicandclinicalcharacteristicsofpatientswithadrenalincidentalomafromasinglecenterinchinaasurvey
AT guweijun baselinedemographicandclinicalcharacteristicsofpatientswithadrenalincidentalomafromasinglecenterinchinaasurvey
AT lvzhaohui baselinedemographicandclinicalcharacteristicsofpatientswithadrenalincidentalomafromasinglecenterinchinaasurvey
AT lujuming baselinedemographicandclinicalcharacteristicsofpatientswithadrenalincidentalomafromasinglecenterinchinaasurvey
AT muyiming baselinedemographicandclinicalcharacteristicsofpatientswithadrenalincidentalomafromasinglecenterinchinaasurvey