Cargando…

Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in inferior alveolar nerve block: Effects on the vital signs and onset, and duration of anesthesia

BACKGROUND: This prospective, randomized, double-blind, clinical study was conducted to compare the effects of 4% articaine with 1:100,000 epinephrine (A100) and 4% articaine with 1:200,000 epinephrine (A200) on the vital signs and onset and duration of anesthesia in an inferior alveolar nerve block...

Descripción completa

Detalles Bibliográficos
Autores principales: Lasemi, Esshagh, Sezavar, Mehdi, Habibi, Leyla, Hemmat, Seyfollah, Sarkarat, Farzin, Nematollahi, Zahra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Dental Society of Anesthsiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564155/
https://www.ncbi.nlm.nih.gov/pubmed/28879280
http://dx.doi.org/10.17245/jdapm.2015.15.4.201
_version_ 1783258217901457408
author Lasemi, Esshagh
Sezavar, Mehdi
Habibi, Leyla
Hemmat, Seyfollah
Sarkarat, Farzin
Nematollahi, Zahra
author_facet Lasemi, Esshagh
Sezavar, Mehdi
Habibi, Leyla
Hemmat, Seyfollah
Sarkarat, Farzin
Nematollahi, Zahra
author_sort Lasemi, Esshagh
collection PubMed
description BACKGROUND: This prospective, randomized, double-blind, clinical study was conducted to compare the effects of 4% articaine with 1:100,000 epinephrine (A100) and 4% articaine with 1:200,000 epinephrine (A200) on the vital signs and onset and duration of anesthesia in an inferior alveolar nerve block (IANB). METHODS: In the first appointment, an IANB was performed by injecting A100 or A200 in 1 side of the mouth (right or left) randomly in patients referred for extraction of both their first mandibular molars. In the second appointment, the protocol was repeated and the other anesthetic solution was injected in the side that had not received the block in the previous session. Systolic and diastolic blood pressures (SBP and DBP) and pulse rate were measured during and 5 min after the injection. The onset and duration of anesthesia were also evaluated. Data were analyzed using t-test and Mann-Whitney U-test, and p-value was set at 0.05. RESULTS: SBP and pulse rate changes were slightly more with A100; however, DBP changes were more with A200, although the differences were not significant (P > 0.05). There were no statistically significant differences in the parameters evaluated in this study. The onset and duration of anesthesia, and the changes in SBP, DBP, and pulse rate during and 5 min after the injection were the same in both the groups. CONCLUSIONS: For an IANB, A200 and A100 were equally efficient and successful in producing the block. Epinephrine concentration did not influence the effects of 4% articaine.
format Online
Article
Text
id pubmed-5564155
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher The Korean Dental Society of Anesthsiology
record_format MEDLINE/PubMed
spelling pubmed-55641552017-09-06 Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in inferior alveolar nerve block: Effects on the vital signs and onset, and duration of anesthesia Lasemi, Esshagh Sezavar, Mehdi Habibi, Leyla Hemmat, Seyfollah Sarkarat, Farzin Nematollahi, Zahra J Dent Anesth Pain Med Original Article BACKGROUND: This prospective, randomized, double-blind, clinical study was conducted to compare the effects of 4% articaine with 1:100,000 epinephrine (A100) and 4% articaine with 1:200,000 epinephrine (A200) on the vital signs and onset and duration of anesthesia in an inferior alveolar nerve block (IANB). METHODS: In the first appointment, an IANB was performed by injecting A100 or A200 in 1 side of the mouth (right or left) randomly in patients referred for extraction of both their first mandibular molars. In the second appointment, the protocol was repeated and the other anesthetic solution was injected in the side that had not received the block in the previous session. Systolic and diastolic blood pressures (SBP and DBP) and pulse rate were measured during and 5 min after the injection. The onset and duration of anesthesia were also evaluated. Data were analyzed using t-test and Mann-Whitney U-test, and p-value was set at 0.05. RESULTS: SBP and pulse rate changes were slightly more with A100; however, DBP changes were more with A200, although the differences were not significant (P > 0.05). There were no statistically significant differences in the parameters evaluated in this study. The onset and duration of anesthesia, and the changes in SBP, DBP, and pulse rate during and 5 min after the injection were the same in both the groups. CONCLUSIONS: For an IANB, A200 and A100 were equally efficient and successful in producing the block. Epinephrine concentration did not influence the effects of 4% articaine. The Korean Dental Society of Anesthsiology 2015-12 2015-12-31 /pmc/articles/PMC5564155/ /pubmed/28879280 http://dx.doi.org/10.17245/jdapm.2015.15.4.201 Text en Copyright © 2015 Journal of Dental Anesthesia and Pain Medicine http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lasemi, Esshagh
Sezavar, Mehdi
Habibi, Leyla
Hemmat, Seyfollah
Sarkarat, Farzin
Nematollahi, Zahra
Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in inferior alveolar nerve block: Effects on the vital signs and onset, and duration of anesthesia
title Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in inferior alveolar nerve block: Effects on the vital signs and onset, and duration of anesthesia
title_full Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in inferior alveolar nerve block: Effects on the vital signs and onset, and duration of anesthesia
title_fullStr Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in inferior alveolar nerve block: Effects on the vital signs and onset, and duration of anesthesia
title_full_unstemmed Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in inferior alveolar nerve block: Effects on the vital signs and onset, and duration of anesthesia
title_short Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in inferior alveolar nerve block: Effects on the vital signs and onset, and duration of anesthesia
title_sort articaine (4%) with epinephrine (1:100,000 or 1:200,000) in inferior alveolar nerve block: effects on the vital signs and onset, and duration of anesthesia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564155/
https://www.ncbi.nlm.nih.gov/pubmed/28879280
http://dx.doi.org/10.17245/jdapm.2015.15.4.201
work_keys_str_mv AT lasemiesshagh articaine4withepinephrine1100000or1200000ininferioralveolarnerveblockeffectsonthevitalsignsandonsetanddurationofanesthesia
AT sezavarmehdi articaine4withepinephrine1100000or1200000ininferioralveolarnerveblockeffectsonthevitalsignsandonsetanddurationofanesthesia
AT habibileyla articaine4withepinephrine1100000or1200000ininferioralveolarnerveblockeffectsonthevitalsignsandonsetanddurationofanesthesia
AT hemmatseyfollah articaine4withepinephrine1100000or1200000ininferioralveolarnerveblockeffectsonthevitalsignsandonsetanddurationofanesthesia
AT sarkaratfarzin articaine4withepinephrine1100000or1200000ininferioralveolarnerveblockeffectsonthevitalsignsandonsetanddurationofanesthesia
AT nematollahizahra articaine4withepinephrine1100000or1200000ininferioralveolarnerveblockeffectsonthevitalsignsandonsetanddurationofanesthesia