Leukemic Ischemia: A Case of Myocardial Infarction Secondary to Leukemic Cardiac Involvement

We report a case of a 39-year-old male who presented to the emergency department with acute chest pain while being in remission from T-cell acute lymphoblastic leukemia (T-ALL). Cardiac markers were elevated and EKG revealed ischemic changes compatible with acute myocardial ischemia. Coronary comput...

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Detalles Bibliográficos
Autores principales: Fursevich, Dzmitry, Zuchowski, Colin, Limback, Joseph, Kendall, Melissa, Ramirez, Ashley, Fanaian, Naim, Burt, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564183/
https://www.ncbi.nlm.nih.gov/pubmed/28848680
http://dx.doi.org/10.1155/2017/7298347
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author Fursevich, Dzmitry
Zuchowski, Colin
Limback, Joseph
Kendall, Melissa
Ramirez, Ashley
Fanaian, Naim
Burt, Jeremy
author_facet Fursevich, Dzmitry
Zuchowski, Colin
Limback, Joseph
Kendall, Melissa
Ramirez, Ashley
Fanaian, Naim
Burt, Jeremy
author_sort Fursevich, Dzmitry
collection PubMed
description We report a case of a 39-year-old male who presented to the emergency department with acute chest pain while being in remission from T-cell acute lymphoblastic leukemia (T-ALL). Cardiac markers were elevated and EKG revealed ischemic changes compatible with acute myocardial ischemia. Coronary computed tomography angiography (CCTA) showed calcium-free coronary arteries and soft tissue myocardial infiltration suggestive of cardiac leukemia. A bone marrow biopsy confirmed recurrence of T-ALL, and patient was successfully treated with chemotherapy. We discuss the prospective diagnosis of myopericardial leukemic involvement and the role of CCTA in diagnosis and perform a literature review.
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spelling pubmed-55641832017-08-28 Leukemic Ischemia: A Case of Myocardial Infarction Secondary to Leukemic Cardiac Involvement Fursevich, Dzmitry Zuchowski, Colin Limback, Joseph Kendall, Melissa Ramirez, Ashley Fanaian, Naim Burt, Jeremy Case Rep Cardiol Case Report We report a case of a 39-year-old male who presented to the emergency department with acute chest pain while being in remission from T-cell acute lymphoblastic leukemia (T-ALL). Cardiac markers were elevated and EKG revealed ischemic changes compatible with acute myocardial ischemia. Coronary computed tomography angiography (CCTA) showed calcium-free coronary arteries and soft tissue myocardial infiltration suggestive of cardiac leukemia. A bone marrow biopsy confirmed recurrence of T-ALL, and patient was successfully treated with chemotherapy. We discuss the prospective diagnosis of myopericardial leukemic involvement and the role of CCTA in diagnosis and perform a literature review. Hindawi 2017 2017-08-07 /pmc/articles/PMC5564183/ /pubmed/28848680 http://dx.doi.org/10.1155/2017/7298347 Text en Copyright © 2017 Dzmitry Fursevich et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Fursevich, Dzmitry
Zuchowski, Colin
Limback, Joseph
Kendall, Melissa
Ramirez, Ashley
Fanaian, Naim
Burt, Jeremy
Leukemic Ischemia: A Case of Myocardial Infarction Secondary to Leukemic Cardiac Involvement
title Leukemic Ischemia: A Case of Myocardial Infarction Secondary to Leukemic Cardiac Involvement
title_full Leukemic Ischemia: A Case of Myocardial Infarction Secondary to Leukemic Cardiac Involvement
title_fullStr Leukemic Ischemia: A Case of Myocardial Infarction Secondary to Leukemic Cardiac Involvement
title_full_unstemmed Leukemic Ischemia: A Case of Myocardial Infarction Secondary to Leukemic Cardiac Involvement
title_short Leukemic Ischemia: A Case of Myocardial Infarction Secondary to Leukemic Cardiac Involvement
title_sort leukemic ischemia: a case of myocardial infarction secondary to leukemic cardiac involvement
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564183/
https://www.ncbi.nlm.nih.gov/pubmed/28848680
http://dx.doi.org/10.1155/2017/7298347
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