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Zinc-finger protein 545 is inactivated due to promoter methylation and functions as a tumor suppressor through the Wnt/β-catenin, PI3K/AKT and MAPK/ERK signaling pathways in colorectal cancer

The transcription factor, zinc-finger protein 545 (ZNF545), that belongs to the Kruppel-associated box zinc-finger protein (KRAB-ZFP) family, acts as a tumor suppressor and is inactivated by promoter methylation in cancers such as nasopharyngeal carcinoma, breast cancer, and gastric cancer, but its...

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Detalles Bibliográficos
Autores principales: Xiang, Shili, Xiang, Tingxiu, Xiao, Qian, Li, Yunhai, Shao, Bianfei, Luo, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564408/
https://www.ncbi.nlm.nih.gov/pubmed/28677721
http://dx.doi.org/10.3892/ijo.2017.4064