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IRF5 is elevated in childhood-onset SLE and regulated by histone acetyltransferase and histone deacetylase inhibitors
Interferon regulatory factor 5 (IRF5) plays a critical role in the induction of type I interferon, proinflammatory cytokines and chemokines, and participates in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus (SLE). However, the relationship between IRF5 and childhood-on...
Autores principales: | Shu, Jin, Li, Ling, Zhou, Lan-Bo, Qian, Jun, Fan, Zhi-Dan, Zhuang, Li-Li, Wang, Lu-Lu, Jin, Rui, Yu, Hai-Guo, Zhou, Guo-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564555/ https://www.ncbi.nlm.nih.gov/pubmed/28525378 http://dx.doi.org/10.18632/oncotarget.17586 |
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