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IRF5 is elevated in childhood-onset SLE and regulated by histone acetyltransferase and histone deacetylase inhibitors

Interferon regulatory factor 5 (IRF5) plays a critical role in the induction of type I interferon, proinflammatory cytokines and chemokines, and participates in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus (SLE). However, the relationship between IRF5 and childhood-on...

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Detalles Bibliográficos
Autores principales: Shu, Jin, Li, Ling, Zhou, Lan-Bo, Qian, Jun, Fan, Zhi-Dan, Zhuang, Li-Li, Wang, Lu-Lu, Jin, Rui, Yu, Hai-Guo, Zhou, Guo-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564555/
https://www.ncbi.nlm.nih.gov/pubmed/28525378
http://dx.doi.org/10.18632/oncotarget.17586

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