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The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation
Low-grade gliomas are one of the most common brain tumors in children, where they frequently form within the optic pathway (optic pathway gliomas; OPGs). Since many OPGs occur in the context of the Neurofibromatosis Type 1 (NF1) cancer predisposition syndrome, we have previously employed Nf1 genetic...
Autores principales: | Solga, Anne C, Toonen, Joseph A, Pan, Yuan, Cimino, Patrick J, Ma, Yu, Castillon, Guillaume A, Gianino, Scott M, Ellisman, Mark H, Lee, Da Yong, Gutmann, David H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564557/ https://www.ncbi.nlm.nih.gov/pubmed/28525381 http://dx.doi.org/10.18632/oncotarget.17589 |
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