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The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis

Piper longum L. is a well-known traditional antihyperlipidemic medicine in China, containing medicinal constituents of piperine, pipernonaline and piperlonguminine in its fruit. However, the antitumor properties of these constituents have not yet been studied. We found that potassium piperate (GBK),...

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Detalles Bibliográficos
Autores principales: Fan, Lifei, Cao, Xuemin, Yan, Huijuan, Wang, Qian, Tian, Xiaoxia, Zhang, Lan, He, Xiaoyan, Borjihan, Gereltu, Morigen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564562/
https://www.ncbi.nlm.nih.gov/pubmed/28467790
http://dx.doi.org/10.18632/oncotarget.16872