Cargando…
The synthetic antihyperlipidemic drug potassium piperate selectively kills breast cancer cells through inhibiting G1-S-phase transition and inducing apoptosis
Piper longum L. is a well-known traditional antihyperlipidemic medicine in China, containing medicinal constituents of piperine, pipernonaline and piperlonguminine in its fruit. However, the antitumor properties of these constituents have not yet been studied. We found that potassium piperate (GBK),...
Autores principales: | Fan, Lifei, Cao, Xuemin, Yan, Huijuan, Wang, Qian, Tian, Xiaoxia, Zhang, Lan, He, Xiaoyan, Borjihan, Gereltu, Morigen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564562/ https://www.ncbi.nlm.nih.gov/pubmed/28467790 http://dx.doi.org/10.18632/oncotarget.16872 |
Ejemplares similares
-
The antihyperlipidemic drug potassium piperonate impairs the migration and tumorigenesis of breast cancer cells via the upregulation of miR-31
por: Tian, Xiaoxia, et al.
Publicado: (2022) -
Antidiabetic and antihyperlipidemic activity of Piper longum root aqueous extract in STZ induced diabetic rats
por: Nabi, Shaik Abdul, et al.
Publicado: (2013) -
Lysophosphatidic Acid–Induced EGFR Transactivation Promotes Gastric Cancer Cell DNA Replication by Stabilizing Geminin in the S Phase
por: Zhao, Haile, et al.
Publicado: (2021) -
Lysophosphatidic acid suppresses apoptosis of high-grade serous ovarian cancer cells by inducing autophagy activity and promotes cell-cycle progression via EGFR-PI3K/Aurora-A(Thr288)-geminin dual signaling pathways
por: Zhao, Haile, et al.
Publicado: (2022) -
AspC-Mediated Aspartate Metabolism Coordinates the Escherichia coli Cell Cycle
por: Liu, Feng, et al.
Publicado: (2014)