Insulin-like growth factor 2 axis supports the serum-independent growth of malignant rhabdoid tumor and is activated by microenvironment stress

Malignant rhabdoid tumors (MRTs) are rare, lethal, pediatric tumors predominantly found in the kidney, brain and soft tissues. MRTs are driven by loss of tumor suppressor SNF5/INI1/SMARCB1/BAF47. The prognosis of MRT is poor using currently available treatments, so new treatment targets need to be i...

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Detalles Bibliográficos
Autores principales: Li, Ting, Wang, Jin, Liu, Pengfei, Chi, Jiadong, Yan, Han, Lei, Lei, Li, Zexing, Yang, Bing, Wang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564563/
https://www.ncbi.nlm.nih.gov/pubmed/28521298
http://dx.doi.org/10.18632/oncotarget.17617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564563/
https://www.ncbi.nlm.nih.gov/pubmed/28521298
http://dx.doi.org/10.18632/oncotarget.17617

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