Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis

Early release of tumor necrosis factor-alpha (TNF-α) during radiotherapy of thoracic cancers plays an important role in radiation pneumonitis, whose inhibition may provide lung radioprotection. We previously reported radiation inactivates Tristetraprolin (TTP), a negative regulator of TNF-α synthesi...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Pranathi Meda, Shukla, Shirish, Ray, Paramita, Mehra, Rohit, Nyati, Mukesh K, Lawrence, Theodore S, Ray, Dipankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564603/
https://www.ncbi.nlm.nih.gov/pubmed/28548957
http://dx.doi.org/10.18632/oncotarget.17770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564603/
https://www.ncbi.nlm.nih.gov/pubmed/28548957
http://dx.doi.org/10.18632/oncotarget.17770

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