Cargando…

Involvement of p38-βTrCP-Tristetraprolin-TNFα axis in radiation pneumonitis

Early release of tumor necrosis factor-alpha (TNF-α) during radiotherapy of thoracic cancers plays an important role in radiation pneumonitis, whose inhibition may provide lung radioprotection. We previously reported radiation inactivates Tristetraprolin (TTP), a negative regulator of TNF-α synthesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krishnamurthy, Pranathi Meda, Shukla, Shirish, Ray, Paramita, Mehra, Rohit, Nyati, Mukesh K, Lawrence, Theodore S, Ray, Dipankar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564603/ https://www.ncbi.nlm.nih.gov/pubmed/28548957 http://dx.doi.org/10.18632/oncotarget.17770

Ejemplares similares

Tristetraprolin Mediates Radiation-Induced TNF-α Production in Lung Macrophages
por: Ray, Dipankar, et al.
Publicado: (2013)

Small molecule and peptide inhibitors of βTrCP and the βTrCP–NRF2 protein–protein interaction
por: Jaffry, Uzma, et al.
Publicado: (2023)

β-TrCP1 facilitates cell cycle checkpoint activation, DNA repair, and cell survival through ablation of β-TrCP2 in response to genotoxic stress
por: Islam, Sehbanul, et al.
Publicado: (2021)

NORE1A Regulates MDM2 Via β-TrCP
por: Schmidt, M. Lee, et al.
Publicado: (2016)

Structural basis of βTrCP1-associated GLI3 processing
por: Shafique, Shagufta, et al.
Publicado: (2019)

Plk1- and β-TrCP–dependent degradation of Bora controls mitotic progression
por: Seki, Akiko, et al.
Publicado: (2008)

β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H
por: Cheng, Yun, et al.
Publicado: (2016)

Datasets from an interaction proteomics screen for substrates of the SCF(βTrCP) ubiquitin ligase
por: Magliozzi, Roberto, et al.
Publicado: (2015)

The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth
por: Cui, Danrui, et al.
Publicado: (2019)

Revealing β-TrCP activity dynamics in live cells with a genetically encoded biosensor
por: Paul, Debasish, et al.
Publicado: (2022)

SCF(βTrCP)-mediated degradation of SHARP1 in triple-negative breast cancer
por: Enriqué Steinberg, Juliana Haydeé, et al.
Publicado: (2023)

USP7 counteracts SCF(βTrCP)- but not APC(Cdh1)-mediated proteolysis of Claspin
por: Faustrup, Helene, et al.
Publicado: (2009)

SCFβ‐TrCP ubiquitinates CHK1 in an AMPK‐dependent manner in response to glucose deprivation
por: Ma, Ying, et al.
Publicado: (2018)

Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP
por: Tatarskiy, Victor V., et al.
Publicado: (2017)

β-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation
por: Wang, Dongping, et al.
Publicado: (2019)

β-TrCP Inhibition Reduces Prostate Cancer Cell Growth via Upregulation of the Aryl Hydrocarbon Receptor
por: Gluschnaider, Udi, et al.
Publicado: (2010)

Regulation of Interleukin-10 Receptor Ubiquitination and Stability by Beta-TrCP-Containing Ubiquitin E3 Ligase
por: Jiang, Hui, et al.
Publicado: (2011)

PLK1 and β-TrCP-Dependent Ubiquitination and Degradation of Rap1GAP Controls Cell Proliferation
por: Wang, Dejie, et al.
Publicado: (2014)

βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy
por: Herrero-Ruiz, Joaquín, et al.
Publicado: (2014)

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP
por: Bufalieri, Francesca, et al.
Publicado: (2019)

Controlling Nuclear NF-κB Dynamics by β-TrCP—Insights from a Computational Model
por: Benary, Uwe, et al.
Publicado: (2019)

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression
por: Mavrommati, Ioanna, et al.
Publicado: (2018)

F-box Protein βTrCP1 Is a Substrate of Extracellular Signal-regulated Kinase 2
por: Lee, Cheol-Jung, et al.
Publicado: (2021)

TRIB2 desensitizes ferroptosis via βTrCP-mediated TFRC ubiquitiantion in liver cancer cells
por: Guo, Susu, et al.
Publicado: (2021)

β-TrCP is dispensable for Vpu's ability to overcome the CD317/Tetherin-imposed restriction to HIV-1 release
por: Tervo, Hanna-Mari, et al.
Publicado: (2011)

Plk1 regulates mitotic Aurora A function through βTrCP-dependent degradation of hBora
por: Chan, Eunice H. Y., et al.
Publicado: (2008)

Vaccinia virus protein A49 activates Wnt signalling by targetting the E3 ligase β-TrCP
por: Maluquer de Motes, Carlos, et al.
Publicado: (2017)

Ribosomal protein S27-like regulates autophagy via the β-TrCP-DEPTOR-mTORC1 axis
por: Xiong, Xiufang, et al.
Publicado: (2018)

MEK nuclear localization promotes YAP stability via sequestering β-TrCP in KRAS mutant cancer cells
por: Xu, Huanji, et al.
Publicado: (2019)

CD147 confers temozolomide resistance of glioma cells via the regulation of β-TrCP/Nrf2 pathway
por: Bu, Xin, et al.
Publicado: (2021)

Correction: TRIB2 desensitizes ferroptosis via βTrCP-mediated TFRC ubiquitiantion in liver cancer cells
por: Guo, Susu, et al.
Publicado: (2021)

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking
por: Mitchell, Richard S., et al.
Publicado: (2009)

Erioflorin Stabilizes the Tumor Suppressor Pdcd4 by Inhibiting Its Interaction with the E3-ligase β-TrCP1
por: Blees, Johanna S., et al.
Publicado: (2012)

GSK-3β phosphorylation-dependent degradation of ZNF281 by β-TrCP2 suppresses colorectal cancer progression
por: Zhu, Yuekun, et al.
Publicado: (2017)

βTrCP is Required for HIV-1 Vpu Modulation of CD4, GaLV Env, and BST-2/Tetherin
por: Song, Yul Eum, et al.
Publicado: (2018)

GSK3-β Stimulates Claspin Degradation via β-TrCP Ubiquitin Ligase and Alters Cancer Cell Survival
por: Cabrera, Elisa, et al.
Publicado: (2019)

ER-stress promotes VHL-independent degradation of hypoxia-inducible factors via FBXW1A/βTrCP
por: Mennerich, Daniela, et al.
Publicado: (2022)

TRIM67 Suppresses TNFalpha-Triggered NF-kB Activation by Competitively Binding Beta-TrCP to IkBa
por: Fan, Wenchun, et al.
Publicado: (2022)

Regulated Degradation of the HIV-1 Vpu Protein through a βTrCP-Independent Pathway Limits the Release of Viral Particles
por: Estrabaud, Emilie, et al.
Publicado: (2007)

USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy
por: Wang, Yi-Chang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_cokqe1ca36i28vn7js5padcdhl