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HIF-2α promotes the formation of vasculogenic mimicry in pancreatic cancer by regulating the binding of Twist1 to the VE-cadherin promoter
Vasculogenic mimicry (VM) is a blood supply modality that occurs independently of endothelial cell angiogenesis. Hypoxia and the epithelial-mesenchymal transition (EMT) induce VM formation by remodeling the extracellular matrix. Our previous study demonstrated that hypoxia-inducible factor-2 alpha (...
Autores principales: | Yang, Jian, Zhu, Dong-Ming, Zhou, Xiao-Gang, Yin, Ni, Zhang, Yi, Zhang, Zi-Xiang, Li, De-Chun, Zhou, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564606/ https://www.ncbi.nlm.nih.gov/pubmed/28599281 http://dx.doi.org/10.18632/oncotarget.17999 |
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