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Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy

Radical surgical resection remains the only effective treatment for advanced pancreatic cancer. Effective protocols for recovery from post-operative complications that result in high rates of morbidity and mortality are therefore essential. The enhanced recovery after surgery (ERAS) protocol is an i...

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Autores principales: Deng, Xiaxing, Cheng, Xi, Huo, Zhen, Shi, Yuan, Jin, Zhijian, Feng, Haoran, Wang, Yue, Wen, Chenlei, Qian, Hao, Zhao, Ren, Qiu, Weihua, Shen, Baiyong, Peng, Chenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564609/
https://www.ncbi.nlm.nih.gov/pubmed/28615506
http://dx.doi.org/10.18632/oncotarget.18092
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author Deng, Xiaxing
Cheng, Xi
Huo, Zhen
Shi, Yuan
Jin, Zhijian
Feng, Haoran
Wang, Yue
Wen, Chenlei
Qian, Hao
Zhao, Ren
Qiu, Weihua
Shen, Baiyong
Peng, Chenghong
author_facet Deng, Xiaxing
Cheng, Xi
Huo, Zhen
Shi, Yuan
Jin, Zhijian
Feng, Haoran
Wang, Yue
Wen, Chenlei
Qian, Hao
Zhao, Ren
Qiu, Weihua
Shen, Baiyong
Peng, Chenghong
author_sort Deng, Xiaxing
collection PubMed
description Radical surgical resection remains the only effective treatment for advanced pancreatic cancer. Effective protocols for recovery from post-operative complications that result in high rates of morbidity and mortality are therefore essential. The enhanced recovery after surgery (ERAS) protocol is an interdisciplinary multimodal concept based on modern anesthesia and analgesia combined with other fast rehabilitation parameters. It was first applied in the field of elective colorectal surgery, and eventually extended to several surgical diseases. In this study, we investigated the feasibility and safety of implementing the ERAS protocol in patients undergoing pancreaticoduodenectomy (PD). We randomly divided 159 patients who underwent PD into two groups who were managed using either ERAS or the conventional protocol. We observed that in those treated with the ERAS protocol several post-operative recovery factors were greatly improved, and there were no complications requiring readmission. We therefore propose that ERAS can improve post-operative recovery of PD patients and shorten the waiting time to chemotherapy, which may improve the overall survival of surgically treated pancreatic cancer patients.
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spelling pubmed-55646092017-08-23 Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy Deng, Xiaxing Cheng, Xi Huo, Zhen Shi, Yuan Jin, Zhijian Feng, Haoran Wang, Yue Wen, Chenlei Qian, Hao Zhao, Ren Qiu, Weihua Shen, Baiyong Peng, Chenghong Oncotarget Research Paper Radical surgical resection remains the only effective treatment for advanced pancreatic cancer. Effective protocols for recovery from post-operative complications that result in high rates of morbidity and mortality are therefore essential. The enhanced recovery after surgery (ERAS) protocol is an interdisciplinary multimodal concept based on modern anesthesia and analgesia combined with other fast rehabilitation parameters. It was first applied in the field of elective colorectal surgery, and eventually extended to several surgical diseases. In this study, we investigated the feasibility and safety of implementing the ERAS protocol in patients undergoing pancreaticoduodenectomy (PD). We randomly divided 159 patients who underwent PD into two groups who were managed using either ERAS or the conventional protocol. We observed that in those treated with the ERAS protocol several post-operative recovery factors were greatly improved, and there were no complications requiring readmission. We therefore propose that ERAS can improve post-operative recovery of PD patients and shorten the waiting time to chemotherapy, which may improve the overall survival of surgically treated pancreatic cancer patients. Impact Journals LLC 2017-05-23 /pmc/articles/PMC5564609/ /pubmed/28615506 http://dx.doi.org/10.18632/oncotarget.18092 Text en Copyright: © 2017 Deng et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (http://creativecommons.org/licenses/by/3.0/) (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Paper
Deng, Xiaxing
Cheng, Xi
Huo, Zhen
Shi, Yuan
Jin, Zhijian
Feng, Haoran
Wang, Yue
Wen, Chenlei
Qian, Hao
Zhao, Ren
Qiu, Weihua
Shen, Baiyong
Peng, Chenghong
Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy
title Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy
title_full Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy
title_fullStr Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy
title_full_unstemmed Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy
title_short Modified protocol for enhanced recovery after surgery is beneficial for Chinese cancer patients undergoing pancreaticoduodenectomy
title_sort modified protocol for enhanced recovery after surgery is beneficial for chinese cancer patients undergoing pancreaticoduodenectomy
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564609/
https://www.ncbi.nlm.nih.gov/pubmed/28615506
http://dx.doi.org/10.18632/oncotarget.18092
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