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Co-targeting of IGF1R/mTOR pathway by miR-497 and miR-99a impairs hepatocellular carcinoma development

Persistent activation of IGF1R/mTOR signaling pathway plays crucial role in the development of hepatocellular carcinoma (HCC). Therefore, our goal was to elucidate microRNAs (miRNAs) targeting IGF1R/mTOR and the therapeutic potential of single or dual miRNA on HCC development. In this study, we foun...

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Detalles Bibliográficos
Autores principales:	Cheng, Henghui, Xue, Jin, Yang, Shouhua, Chen, Yaobin, Wang, Yu, Zhu, Yuanli, Wang, Xiaoyan, Kuang, Dong, Ruan, Qiurong, Duan, Yaqi, Wang, Guoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564620/ https://www.ncbi.nlm.nih.gov/pubmed/28624790 http://dx.doi.org/10.18632/oncotarget.18207

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