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A novel method to generate Salmonella Typhi Ty21a ghosts exploiting the λ phage holin-endolysin system

Human typhoid fever caused by Salmonella Typhi still poses a severe global disease burden in developing countries despite the availability of commercial vaccines. In this study, we constructed a non-living S. Typhi Ty21a vaccine candidate by employing a lambda (λ) phage-derived holin-endolysin syste...

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Detalles Bibliográficos
Autores principales: Won, Gayeon, Kim, Boram, Lee, John Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564637/
https://www.ncbi.nlm.nih.gov/pubmed/28637001
http://dx.doi.org/10.18632/oncotarget.18383