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A novel method to generate Salmonella Typhi Ty21a ghosts exploiting the λ phage holin-endolysin system
Human typhoid fever caused by Salmonella Typhi still poses a severe global disease burden in developing countries despite the availability of commercial vaccines. In this study, we constructed a non-living S. Typhi Ty21a vaccine candidate by employing a lambda (λ) phage-derived holin-endolysin syste...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564637/ https://www.ncbi.nlm.nih.gov/pubmed/28637001 http://dx.doi.org/10.18632/oncotarget.18383 |