Protein drug target activation homogeneity in the face of intra-tumor heterogeneity: implications for precision medicine

Introduction: Recent studies indicated tumors may be comprised of heterogeneous molecular subtypes and incongruent molecular portraits may emerge if different areas of the tumor are sampled. This study explored the impact of intra-tumoral heterogeneity in terms of activation/phosphorylation of FDA a...

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Detalles Bibliográficos
Autores principales: Parasido, Erika Maria, Silvestri, Alessandra, Canzonieri, Vincenzo, Belluco, Claudio, Diodoro, Maria Grazia, Milione, Massimo, Melotti, Flavia, De Maria, Ruggero, Liotta, Lance, Petricoin, Emanuel F., Pierobon, Mariaelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564706/
https://www.ncbi.nlm.nih.gov/pubmed/28159918
http://dx.doi.org/10.18632/oncotarget.14019

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