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Activation of the ATF2/CREB-PGC-1α pathway by metformin leads to dopaminergic neuroprotection

Progressive dopaminergic neurodegeneration is responsible for the canonical motor deficits in Parkinson's disease (PD). The widely prescribed anti-diabetic medicine metformin is effective in preventing neurodegeneration in animal models; however, despite the significant potential of metformin f...

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Detalles Bibliográficos
Autores principales:	Kang, Hojin, Khang, Rin, Ham, Sangwoo, Jeong, Ga Ram, Kim, Hyojung, Jo, Minkyung, Lee, Byoung Dae, Lee, Yun Il, Jo, Areum, Park, ChiHu, Kim, Hyein, Seo, Jeongkon, Paek, Sun Ha, Lee, Yun-Song, Choi, Jeong-Yun, Lee, Yunjong, Shin, Joo-Ho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564711/ https://www.ncbi.nlm.nih.gov/pubmed/28611284 http://dx.doi.org/10.18632/oncotarget.18122

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