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Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas
Hepatocellular Carcinoma (HCC) commonly develops in chronically damaged liver tissues. The resulting regenerative and inflammatory processes create an adverse milieu that promotes tumor-initiation and progression. A better understanding of the hepatic tumor-microenvironment interaction might infer p...
Autores principales: | Castven, Darko, Fischer, Michael, Becker, Diana, Heinrich, Stefan, Andersen, Jesper B., Strand, Dennis, Sprinzl, Martin F., Strand, Susanne, Czauderna, Carolin, Heilmann-Heimbach, Stefanie, Roessler, Stephanie, Weinmann, Arndt, Wörns, Marcus A., Thorgeirsson, Snorri S., Galle, Peter R., Matter, Matthias S., Lang, Hauke, Marquardt, Jens U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564717/ https://www.ncbi.nlm.nih.gov/pubmed/28415775 http://dx.doi.org/10.18632/oncotarget.16231 |
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