GLI1 inhibitor GANT61 exhibits antitumor efficacy in T-cell lymphoma cells through down-regulation of p-STAT3 and SOCS3

T-cell lymphomas are lymphoid malignancies with aggressive clinical course and poor prognosis. Increasing evidences suggest that deregulation of signal transducer and activator of transcription-3 (STAT3) and suppressor of cytokine signaling 3 (SOCS3) is associated with the pathogenesis of T-cell lym...

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Detalles Bibliográficos
Autores principales: Geng, Lingyun, Lu, Kang, Li, Peipei, Li, Xinyu, Zhou, Xiangxiang, Li, Ying, Wang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564718/
https://www.ncbi.nlm.nih.gov/pubmed/27275540
http://dx.doi.org/10.18632/oncotarget.9792

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