Cargando…

Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer

Cisplatin resistance remains a major problem in the treatment of lung cancer. We have discovered that cisplatin resistant (CR) lung cancer cells, regardless of the signaling pathway status, share the common parameter which is an increase in reactive oxygen species (ROS) and undergo metabolic reprogr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wangpaichitr, Medhi, Wu, Chunjing, Li, Ying Ying, Nguyen, Dan J.M., Kandemir, Hande, Shah, Sumedh, Chen, Shumei, Feun, Lynn G., Prince, Jeffrey S., Kuo, Macus T., Savaraj, Niramol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564767/ https://www.ncbi.nlm.nih.gov/pubmed/28525376 http://dx.doi.org/10.18632/oncotarget.17568

Ejemplares similares

BRAF inhibitor resistance enhances vulnerability to arginine deprivation in melanoma
por: Li, Ying-Ying, et al.
Publicado: (2016)

N′(1),N′(3)-Dimethyl-N′(1),N′(3)-bis(phenylcarbonothioyl) Propanedihydrazide (Elesclomol) Selectively Kills Cisplatin Resistant Lung Cancer Cells through Reactive Oxygen Species (ROS)
por: Wangpaichitr, Medhi, et al.
Publicado: (2009)

Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin
por: Savaraj, Niramol, et al.
Publicado: (2015)

Degradation of AMPK‐α1 sensitizes BRAF inhibitor‐resistant melanoma cells to arginine deprivation
por: Li, Ying‐Ying, et al.
Publicado: (2017)

Enhancing the Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Signaling and Arginine Deprivation in Melanoma
por: Wu, Chunjing, et al.
Publicado: (2021)

Overcoming cisplatin resistance by mTOR inhibitor in lung cancer
por: Wu, Chunjing, et al.
Publicado: (2005)

Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and Cons for Cancer Therapy
por: Li, Ying-Ying, et al.
Publicado: (2017)

Cisplatin Resistance and Redox-Metabolic Vulnerability: A Second Alteration
por: Wangpaichitr, Medhi, et al.
Publicado: (2021)

The Relationship of Arginine Deprivation, Argininosuccinate Synthetase and Cell Death in Melanoma
por: Savaraj, Niramol, et al.
Publicado: (2007)

Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes
por: Kuo, Macus Tien, et al.
Publicado: (2010)

Phase II trial of SOM230 (pasireotide LAR) in patients with unresectable hepatocellular carcinoma
por: Feun, Lynn G, et al.
Publicado: (2018)

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation
por: Long, Yan, et al.
Publicado: (2016)

Targeting the Proline–Glutamine–Asparagine–Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy
por: Kuo, Macus Tien, et al.
Publicado: (2021)

Procollagen-Like Protein as a Molecular Target in the Treatment of Primary Brain Tumor
por: Wangpaichitr, Medhi, et al.
Publicado: (2002)

Relationship of Metabolic Alterations and PD-L1 Expression in Cisplatin Resistant Lung Cancer
por: Wangpaichitr, M, et al.
Publicado: (2017)

Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors
por: Kuo, Macus Tien, et al.
Publicado: (2019)

The Combination of Arginine Deprivation and 5-Fluorouracil Improves Therapeutic Efficacy in Argininosuccinate Synthetase Negative Hepatocellular Carcinoma
por: Thongkum, Angkana, et al.
Publicado: (2017)

Dual inhibition of IDO1/TDO2 enhances anti-tumor immunity in platinum-resistant non-small cell lung cancer
por: Wu, Chunjing, et al.
Publicado: (2023)

Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals
por: Liang, Zheng Dong, et al.
Publicado: (2013)

Radiofrequency ablation in primary non-small cell lung cancer: What a radiologist needs to know
por: Bhatia, Shivank, et al.
Publicado: (2016)

Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1α Degradation at the ASS1 promoter for ASS1 Derepression
por: Tsai, Wen-Bin, et al.
Publicado: (2017)

Role of Glutathione in the Regulation of Cisplatin Resistance in Cancer Chemotherapy
por: Chen, Helen H. W., et al.
Publicado: (2010)

C‐Jun N‐terminal kinase signalling pathway in response to cisplatin
por: Yan, Dong, et al.
Publicado: (2016)

Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase
por: Feun, L G, et al.
Publicado: (2012)

Synergistic killing of lung cancer cells by cisplatin and radiation via autophagy and apoptosis
por: LIU, MIN, et al.
Publicado: (2014)

Nivolumab to pembrolizumab switch induced a durable melanoma response: A case report
por: Lepir, Tanja, et al.
Publicado: (2019)

Aberrant ROS Served as an Acquired Vulnerability of Cisplatin-Resistant Lung Cancer
por: Xin, Qian, et al.
Publicado: (2022)

ROS-Mediated Cancer Cell Killing through Dietary Phytochemicals
por: NavaneethaKrishnan, Saranya, et al.
Publicado: (2019)

Decreased argininosuccinate synthetase expression in Thai patients with cholangiocarcinoma and the effects of ADI-PEG20 treatment in CCA cell lines
por: Roeksomtawin, Somphon, et al.
Publicado: (2018)

Can the two mechanisms of tumor cell killing by radiation be exploited for therapeutic gain?
por: Chapman, J.D.
Publicado: (2014)

Selective Killing of Cancer Cells by Ashwagandha Leaf Extract and Its Component Withanone Involves ROS Signaling
por: Widodo, Nashi, et al.
Publicado: (2010)

Exploiting phage receptor binding proteins to enable endolysins to kill Gram-negative bacteria
por: Zampara, Athina, et al.
Publicado: (2020)

Exploiting DNA repair defects in triple negative breast cancer to improve cell killing
por: Lee, Kevin J., et al.
Publicado: (2020)

The role of apoptosis in cell killing by cisplatin: a flow cytometric study.
por: Ormerod, M. G., et al.
Publicado: (1994)

Cardiomyopathic mutations in essential light chain reveal mechanisms regulating the super relaxed state of myosin
por: Sitbon, Yoel H., et al.
Publicado: (2021)

Piperlongumine increases the sensitivity of bladder cancer to cisplatin by mitochondrial ROS
por: Pan, Xiaobo, et al.
Publicado: (2022)

Oxidization enhances type I ROS generation of AIE-active zwitterionic photosensitizers for photodynamic killing of drug-resistant bacteria
por: Gong, Jianye, et al.
Publicado: (2023)

Microbial lectome versus host glycolipidome: How pathogens exploit glycosphingolipids to invade, dupe or kill
por: Bereznicka, Anna, et al.
Publicado: (2022)

Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance
por: García-Cano, Jesús, et al.
Publicado: (2015)

Selective killing of cancer cells with a small molecule targeting stress response to ROS
por: Raj, Lakshmi, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_lf40ujqrmc7tk7oqlip1bnq7gd