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Sestrin 2 suppresses cells proliferation through AMPK/mTORC1 pathway activation in colorectal cancer

Sestrin 2 is a conserved antioxidant protein that reduces reactive oxygen species (ROS) and inhibits mammalian target of rapamycin complex 1 (mTORC1). We previously showed that sestrin 2 is abnormally decreased in colorectal cancer (CRC). To elucidate the molecular mechanism behind the potential con...

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Detalles Bibliográficos
Autores principales:	Wei, Jin-Lai, Fang, Min, Fu, Zhong-Xue, Zhang, Shou–Ru, Guo, Jin-Bao, Wang, Rong, Lv, Zhen-Bing, Xiong, Yong-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564770/ https://www.ncbi.nlm.nih.gov/pubmed/28525387 http://dx.doi.org/10.18632/oncotarget.17595

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