Cargando…

Increased expression of IRF8 in tumor cells inhibits the generation of Th17 cells and predicts unfavorable survival of diffuse large B cell lymphoma patients

The immunological pathogenesis of diffuse large B cell lymphoma (DLBCL) remains elusive. Searching for new prognostic markers of DLBCL is a crucial focal point for clinical scientists. The aim of the present study was to examine the prognostic value of interferon regulatory factor 8 (IRF8) expressio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhong, Wei-Jie, Xu, Xin, Zhu, Zhi-Gang, Du, Qing-Hua, Du, Hong, Yang, Li, Ling, Yan-Ying, Xiong, Hua-Bao, Li, Qing-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564805/ https://www.ncbi.nlm.nih.gov/pubmed/28537908 http://dx.doi.org/10.18632/oncotarget.17693

Ejemplares similares

Loss of IRF8 Inhibits the Growth of Diffuse Large B-cell Lymphoma
por: Xu, Yulian, et al.
Publicado: (2015)

Increased interleukin-17A levels promote rituximab resistance by suppressing p53 expression and predict an unfavorable prognosis in patients with diffuse large B cell lymphoma
por: Zhong, Weijie, et al.
Publicado: (2018)

Elevated Frequencies of Circulating Th22 Cell in Addition to Th17 Cell and Th17/Th1 Cell in Patients with Acute Coronary Syndrome
por: Zhang, Lei, et al.
Publicado: (2013)

IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma
por: Elfrink, Suraya, et al.
Publicado: (2022)

IRF4 is required for migration of CD4(+) T cells to the intestine but not for Th2 and Th17 cell maintenance
por: Schmidt, Constantin, et al.
Publicado: (2023)

Transcription factor IRF8 directs a silencing programme for T(H)17 cell differentiation
por: Ouyang, Xinshou, et al.
Publicado: (2011)

A novel prognostic model based on four circulating miRNA in diffuse large B‐cell lymphoma: implications for the roles of MDSC and Th17 cells in lymphoma progression
por: Sun, Rui, et al.
Publicado: (2020)

MUM1/IRF4 Expression Is an Unfavorable Prognostic Factor in B‐Cell Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
por: Ito, Masato, et al.
Publicado: (2002)

High KIF2A expression predicts unfavorable prognosis in diffuse large B cell lymphoma
por: Zhang, Yaping, et al.
Publicado: (2017)

IRF4 rearrangement may predict favorable prognosis in children and young adults with primary head and neck large B‐cell lymphoma
por: Jiang, Xiang‐Nan, et al.
Publicado: (2023)

SPIB and BATF provide alternate determinants of IRF4 occupancy in diffuse large B-cell lymphoma linked to disease heterogeneity
por: Care, Matthew A., et al.
Publicado: (2014)

MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression
por: Jia, Aijun, et al.
Publicado: (2017)

High nuclear expression of STAT3 is associated with unfavorable prognosis in diffuse large B-cell lymphoma
por: ZL, Wu, et al.
Publicado: (2011)

Bone marrow IRF4 level in multiple myeloma: an indicator of peripheral blood Th17 and disease
por: Bai, Hua, et al.
Publicado: (2017)

Effects of 17-DMAG on diffuse large B-cell lymphoma cell apoptosis
por: Li, Jia-Jia, et al.
Publicado: (2017)

Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses
por: Lee, Jihyung, et al.
Publicado: (2020)

Low CCL17 expression associates with unfavorable postoperative prognosis of patients with clear cell renal cell carcinoma
por: Xiong, Ying, et al.
Publicado: (2017)

IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination
por: Kratchmarov, Radomir, et al.
Publicado: (2017)

MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis
por: Vermaat, Joost S., et al.
Publicado: (2020)

Shared and Distinct Functions of the Transcription Factors IRF4 and IRF8 in Myeloid Cell Development
por: Yamamoto, Michio, et al.
Publicado: (2011)

Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming
por: McDaniel, Margaret M., et al.
Publicado: (2020)

IRF4 is Correlated with the Conversion to a Th17-Like Phenotype in Regulatory T Cells from the Malignant Pleural Effusion
por: Yu, Wenqing, et al.
Publicado: (2021)

Inflammation marker ESR is effective in predicting outcome of diffuse large B-cell lymphoma
por: Wu, Shuang, et al.
Publicado: (2018)

Treg/Th17 Cell Balance in Patients with Hepatitis B Virus-Related Acute-on-Chronic Liver Failure at Different Disease Stages
por: Tan, Nian-Hua, et al.
Publicado: (2021)

T Cell Vaccination Inhibits Th1/Th17/Tfh Frequencies and Production of Autoantibodies in Collagen-Induced Arthritis
por: Li, Shan, et al.
Publicado: (2013)

Plasmodium yoelii 17XL infection modified maturation and function of dendritic cells by skewing Tregs and amplificating Th17
por: Chen, Guang, et al.
Publicado: (2020)

Primary diffuse large B-cell lymphoma of orbit: A population-based analysis
por: Chen, Yu-Qing, et al.
Publicado: (2022)

Expression IRF/MUM1>25% Predictor to Three-year Survival of Diffuse Large B Cell Lymphoma in the Immunochemotherapy Era
por: Sofo-Hafizovic, Alma, et al.
Publicado: (2016)

Mutations or copy number losses of CD58 and TP53 genes in diffuse large B cell lymphoma are independent unfavorable prognostic factors
por: Cao, Yang, et al.
Publicado: (2016)

MicroRNA-155 Modulates Treg and Th17 Cells Differentiation and Th17 Cell Function by Targeting SOCS1
por: Yao, Rui, et al.
Publicado: (2012)

A Novel Epitope from CD22 Regulates Th1 and Th17 Cell Function in Systemic Lupus Erythematosus
por: Yuan, Jing, et al.
Publicado: (2013)

Anaplastic lymphoma kinase-positive large B-cell lymphoma: Clinico-pathological study of 17 cases with review of literature
por: Jiang, Xiang-Nan, et al.
Publicado: (2017)

Recurrent translocations involving the IRF4 oncogene locus in peripheral T-cell lymphomas
por: Feldman, Andrew L., et al.
Publicado: (2008)

Aberrant Circulating Th17 Cells in Patients with B-Cell Non-Hodgkin’s Lymphoma
por: Lu, Ting, et al.
Publicado: (2016)

Effect of interleukin 21 and its receptor on CD8(+) T cells in the pathogenesis of diffuse large B-cell lymphoma
por: CHA, ZHANSHAN, et al.
Publicado: (2014)

IRF8-dependent molecular complexes control the Th9 transcriptional program
por: Humblin, Etienne, et al.
Publicado: (2017)

Defining Diffuse Large B-Cell Lymphoma Immunotypes by CD8+ T Cells and Natural Killer Cells
por: Qi, Jing, et al.
Publicado: (2022)

Increased Frequencies of Th22 Cells as well as Th17 Cells in the Peripheral Blood of Patients with Ankylosing Spondylitis and Rheumatoid Arthritis
por: Zhang, Lei, et al.
Publicado: (2012)

Up-Regulation of Intestinal Epithelial Cell Derived IL-7 Expression by Keratinocyte Growth Factor through STAT1/IRF-1, IRF-2 Pathway
por: Cai, Yu-Jiao, et al.
Publicado: (2013)

Tagging Single Nucleotide Polymorphisms in the IRF1 and IRF8 Genes and Tuberculosis Susceptibility
por: Ding, Shiping, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_12p8891bvlc3umc39lb2vn1f4f