Cargando…

Maintenance of cancer stemness by miR-196b-5p contributes to chemoresistance of colorectal cancer cells via activating STAT3 signaling pathway

Emerging studies indicated that cancer stem cells represent a subpopulation of cells within the tumor that is responsible for chemotherapeutic resistance. However, the underlying mechanism is still not clarified yet. Here we report that miR-196b-5p is dramatically upregulated in CRC tissues and high...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Dong, Lin, Bihua, Zhang, Xin, Peng, Yao, Ye, Ziyu, Ma, Yan, Liang, Yangfang, Cao, Longbin, Li, Xiangyong, Li, Ronggang, Sun, Lixia, Liu, Qiongru, Wu, Jinhua, Zhou, Keyuan, Zeng, Jincheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564809/
https://www.ncbi.nlm.nih.gov/pubmed/28591704
http://dx.doi.org/10.18632/oncotarget.17971