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Intra-tumour molecular heterogeneity of clear cell renal cell carcinoma reveals the diversity of the response to targeted therapies using patient-derived xenograft models

Inter- and intra-tumour molecular heterogeneity is increasingly recognized in clear cell renal cell carcinoma (ccRCC). It may partially explain the diversity of responses to targeted therapies and the various clinical outcomes. In this study, a 56-year-old male ccRCC patient with multiple metastases...

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Detalles Bibliográficos
Autores principales: Hong, Baoan, Yang, Yong, Guo, Sheng, Duoerkun, Shayiremu, Deng, Xiaohu, Chen, Dawei, Yu, Shijun, Qian, Wubin, Li, Qixiang, Li, Qing, Gong, Kan, Zhang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564811/
https://www.ncbi.nlm.nih.gov/pubmed/28548943
http://dx.doi.org/10.18632/oncotarget.17765